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Book Details :
Published on: 2012-12-06
Released on: 2012-12-06
Original language:

In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology. PPT Anticancer drugs PowerPoint presentation free to ... Buy Anticancer Drugs - Use Cytarabine Sutent Medicine to treat Cancer - Cancer is also known as a malignant tumor. Cancer is a group of diseases relating abnormal ... Conferences and Meetings on Molecular Biology Conferences and Meetings on Molecular Biology. Conference-Service.com offers as part of our business activities a directory of upcoming scientific and technical ... MBB News - About the Department - Molecular Biology and ... MBB News. If you have interesting news you want to share please send it to m.williamson@sheffield.ac.uk. University Open Days. The University's next Open Day will be ... Antimicrobials for Bacteria - Inicial UFRGS Novel strategies in antibacterial drug development ref: antivirulence-directed therapy; target virulent bacteria; requires discovery of a lethal target present only ... OMIM Entry - 210900 - BLOOM SYNDROME; BLM A number sign () is used with this entry because Bloom syndrome (BLM) is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase ... Design Synthesis and Evaluation of Bifunctional ... Supramolecular and Material Chemistry Lab School of Physical Sciences Jawaharlal Nehru University New Mehrauli Road 110067 New Delhi India School of Life ... Curcumin 95% Turmeric Extract Capsules Has the bioavailability of Curcumin 95% been studied? "In a human clinical trial 3.6 g of Curcumin via oral route was found to produce a plasma curcumin level of 11 ... Quinolones- Infectious Disease and Antimicrobial Agents A great deal of attention has been directed to cardiovascular toxicity induced by some quinolones. Several quinolones have been linked to QT prolongation and ... DNA repair - Wikipedia DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells both normal ... DNA - Wikipedia DNA is a long polymer made from repeating units called nucleotides. The structure of DNA is dynamic along its length being capable of coiling into tight loops and ...
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